Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADIPOQ | AGRP | ENSMMUP00000055436 | ENSMMUP00000071178 | Adiponectin, C1Q and collagen domain containing. | Agouti related neuropeptide. | 0.582 |
| ADIPOQ | GHRL | ENSMMUP00000055436 | ENSMMUP00000062710 | Adiponectin, C1Q and collagen domain containing. | Ghrelin and obestatin prepropeptide. | 0.787 |
| ADIPOQ | INS | ENSMMUP00000055436 | ENSMMUP00000037777 | Adiponectin, C1Q and collagen domain containing. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.936 |
| ADIPOQ | LEP | ENSMMUP00000055436 | ENSMMUP00000007035 | Adiponectin, C1Q and collagen domain containing. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.972 |
| ADIPOQ | LEPR | ENSMMUP00000055436 | ENSMMUP00000004351 | Adiponectin, C1Q and collagen domain containing. | Leptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] | 0.700 |
| ADIPOQ | NPY | ENSMMUP00000055436 | ENSMMUP00000070707 | Adiponectin, C1Q and collagen domain containing. | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.486 |
| ADIPOQ | POMC | ENSMMUP00000055436 | ENSMMUP00000075833 | Adiponectin, C1Q and collagen domain containing. | Uncharacterized protein. | 0.496 |
| AGRP | ADIPOQ | ENSMMUP00000071178 | ENSMMUP00000055436 | Agouti related neuropeptide. | Adiponectin, C1Q and collagen domain containing. | 0.582 |
| AGRP | GHRL | ENSMMUP00000071178 | ENSMMUP00000062710 | Agouti related neuropeptide. | Ghrelin and obestatin prepropeptide. | 0.934 |
| AGRP | INS | ENSMMUP00000071178 | ENSMMUP00000037777 | Agouti related neuropeptide. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.834 |
| AGRP | LEP | ENSMMUP00000071178 | ENSMMUP00000007035 | Agouti related neuropeptide. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.946 |
| AGRP | LEPR | ENSMMUP00000071178 | ENSMMUP00000004351 | Agouti related neuropeptide. | Leptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] | 0.835 |
| AGRP | NPY | ENSMMUP00000071178 | ENSMMUP00000070707 | Agouti related neuropeptide. | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.955 |
| AGRP | POMC | ENSMMUP00000071178 | ENSMMUP00000075833 | Agouti related neuropeptide. | Uncharacterized protein. | 0.967 |
| AGRP | PRL | ENSMMUP00000071178 | ENSMMUP00000027172 | Agouti related neuropeptide. | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. | 0.420 |
| EPO | INS | ENSMMUP00000030108 | ENSMMUP00000037777 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.634 |
| EPO | LEP | ENSMMUP00000030108 | ENSMMUP00000007035 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.953 |
| EPO | LEPR | ENSMMUP00000030108 | ENSMMUP00000004351 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Leptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] | 0.701 |
| EPO | PRL | ENSMMUP00000030108 | ENSMMUP00000027172 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. | 0.929 |
| EPO | THPO | ENSMMUP00000030108 | ENSMMUP00000009876 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Thrombopoietin. | 0.972 |
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