Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4001 aa)    
Predicted Functional Partners:
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.997
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.997
WDR5
WD repeat domain 5.
   
 0.996
MEN1
Menin isoform 2.
    
 0.995
KMT2D
Lysine methyltransferase 2D.
   
0.986
WDR5B
Uncharacterized protein.
   
 0.985
CREBBP
CREB-binding protein isoform a.
   
 0.975
KMT2B
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
   
0.960
HCFC1
Host cell factor C1.
   
 0.931
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
   
 0.925
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (22%) [HD]