PIK3R5 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGR	LYN	ENSMMUP00000066247	ENSMMUP00000052162	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.941
FGR	PIK3CA	ENSMMUP00000066247	ENSMMUP00000006866	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.818
FGR	PIK3CB	ENSMMUP00000066247	ENSMMUP00000011365	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.820
FGR	PIK3CD	ENSMMUP00000066247	ENSMMUP00000068489	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.810
FGR	PIK3CG	ENSMMUP00000066247	ENSMMUP00000066301	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	0.942
FGR	PIK3R1	ENSMMUP00000066247	ENSMMUP00000015140	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.835
FGR	PIK3R2	ENSMMUP00000066247	ENSMMUP00000004228	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.849
FGR	PIK3R3	ENSMMUP00000066247	ENSMMUP00000060463	Tyrosine-protein kinase.	Uncharacterized protein.	0.818
FGR	PIK3R5	ENSMMUP00000066247	ENSMMUP00000007641	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 5.	0.953
GNG4	PIK3CA	ENSMMUP00000064430	ENSMMUP00000006866	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.843
GNG4	PIK3CB	ENSMMUP00000064430	ENSMMUP00000011365	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.832
GNG4	PIK3CD	ENSMMUP00000064430	ENSMMUP00000068489	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.832
GNG4	PIK3CG	ENSMMUP00000064430	ENSMMUP00000066301	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	0.934
GNG4	PIK3R1	ENSMMUP00000064430	ENSMMUP00000015140	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphoinositide-3-kinase regulatory subunit 1.	0.779
GNG4	PIK3R2	ENSMMUP00000064430	ENSMMUP00000004228	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.754
GNG4	PIK3R3	ENSMMUP00000064430	ENSMMUP00000060463	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Uncharacterized protein.	0.756
GNG4	PIK3R5	ENSMMUP00000064430	ENSMMUP00000007641	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphoinositide-3-kinase regulatory subunit 5.	0.946
LYN	FGR	ENSMMUP00000052162	ENSMMUP00000066247	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.941
LYN	PIK3CA	ENSMMUP00000052162	ENSMMUP00000006866	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.969
LYN	PIK3CB	ENSMMUP00000052162	ENSMMUP00000011365	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.969