UBA2 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMUP00000072025	KCTD2	ENSMMUP00000072025	ENSMMUP00000034103	Small ubiquitin-related modifier.	Potassium channel tetramerization domain containing 2.	0.679
ENSMMUP00000072025	SAE1	ENSMMUP00000072025	ENSMMUP00000059881	Small ubiquitin-related modifier.	ThiF domain-containing protein.	0.925
ENSMMUP00000072025	SUMO1	ENSMMUP00000072025	ENSMMUP00000045844	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.526
ENSMMUP00000072025	UBA2	ENSMMUP00000072025	ENSMMUP00000007742	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.936
ENSMMUP00000072025	UBE2I	ENSMMUP00000072025	ENSMMUP00000065615	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.907
JPT1	KCTD2	ENSMMUP00000074261	ENSMMUP00000034103	Ubiquitin-like domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.679
JPT1	SAE1	ENSMMUP00000074261	ENSMMUP00000059881	Ubiquitin-like domain-containing protein.	ThiF domain-containing protein.	0.851
JPT1	SUMO1	ENSMMUP00000074261	ENSMMUP00000045844	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.698
JPT1	UBA2	ENSMMUP00000074261	ENSMMUP00000007742	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.863
JPT1	UBE2I	ENSMMUP00000074261	ENSMMUP00000065615	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.911
KCTD2	ENSMMUP00000072025	ENSMMUP00000034103	ENSMMUP00000072025	Potassium channel tetramerization domain containing 2.	Small ubiquitin-related modifier.	0.679
KCTD2	JPT1	ENSMMUP00000034103	ENSMMUP00000074261	Potassium channel tetramerization domain containing 2.	Ubiquitin-like domain-containing protein.	0.679
KCTD2	LOC699185	ENSMMUP00000034103	ENSMMUP00000074231	Potassium channel tetramerization domain containing 2.	Small ubiquitin-related modifier.	0.679
KCTD2	SAE1	ENSMMUP00000034103	ENSMMUP00000059881	Potassium channel tetramerization domain containing 2.	ThiF domain-containing protein.	0.885
KCTD2	SUMO1	ENSMMUP00000034103	ENSMMUP00000045844	Potassium channel tetramerization domain containing 2.	Small ubiquitin-related modifier.	0.868
KCTD2	SUMO3	ENSMMUP00000034103	ENSMMUP00000053383	Potassium channel tetramerization domain containing 2.	Ubiquitin-like domain-containing protein.	0.679
KCTD2	SUMO3-2	ENSMMUP00000034103	ENSMMUP00000002708	Potassium channel tetramerization domain containing 2.	Ubiquitin-like domain-containing protein.	0.679
KCTD2	UBA2	ENSMMUP00000034103	ENSMMUP00000007742	Potassium channel tetramerization domain containing 2.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.867
LOC699185	KCTD2	ENSMMUP00000074231	ENSMMUP00000034103	Small ubiquitin-related modifier.	Potassium channel tetramerization domain containing 2.	0.679
LOC699185	SAE1	ENSMMUP00000074231	ENSMMUP00000059881	Small ubiquitin-related modifier.	ThiF domain-containing protein.	0.925