Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPAG5Sperm associated antigen 5. (1195 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.929
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.928
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.927
NDC80
Kinetochore protein NDC80 homolog.
   
 0.917
KNSTRN
Kinetochore localized astrin (SPAG5) binding protein.
   
 
 0.917
CDCA3
Cell division cycle-associated protein 3.
   
  
 0.915
KIF15
Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.915
TTK
TTK protein kinase.
   
 
 0.911
DLGAP5
DLG associated protein 5.
   
 0.908
KIFC1
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.908
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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