STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTN4Actinin alpha 4. (911 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.990
ACTN1
Actinin alpha 1.
  
0.988
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 0.955
LOC705671
Uncharacterized protein.
   
 0.940
ACTG1
Actin, cytoplasmic 2.
   
 0.940
ZYX
Zyxin.
   
 0.939
CTNNA1
Uncharacterized protein.
   
 0.930
CTNNA3
Catenin alpha-3.
   
 0.930
CTNNA2
Catenin alpha 2.
   
 0.930
SSX2IP
Afadin-and alpha-actinin-binding protein isoform 1.
    
 0.916
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.