Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CDONCell adhesion associated, oncogene regulated. (1339 aa)    
Predicted Functional Partners:
PTCH1
Patched 1.
    
 0.996
BOC
BOC cell adhesion associated, oncogene regulated.
   
0.993
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.992
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.990
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.985
GAS1
Growth arrest specific 1.
   
 0.984
LRP2
LDL receptor related protein 2.
     
 0.919
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.875
CDH2
Cadherin-2 preproprotein; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.833
DLG1
Disks large homolog 1 isoform 2; Belongs to the MAGUK family.
    
 0.779
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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