Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LMO2Uncharacterized protein. (222 aa)    
Predicted Functional Partners:
TAL1
BHLH domain-containing protein.
   
 0.992
LDB1
LIM domain-binding protein 1 isoform 1.
    
 0.987
GATA1
GATA binding protein 1.
    
 0.963
LDB2
LID domain-containing protein.
    
 0.941
GATA2
GATA binding protein 2.
    
 0.863
LYL1
LYL1 basic helix-loop-helix family member.
   
 0.785
MYB
MYB proto-oncogene, transcription factor.
    
 0.766
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.760
POLR2G
S1 domain-containing protein.
    
   0.739
POLR2D
DNA-directed RNA polymerase II subunit RPB4.
    
   0.714
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (42%) [HD]