node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IKBKE | IRF3 | ENSMMUP00000038190 | ENSMMUP00000029942 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | Interferon regulatory factor 3. | 0.931 |
IKBKE | IRF7 | ENSMMUP00000038190 | ENSMMUP00000009317 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | Interferon regulatory factor 7. | 0.961 |
IKBKE | MAVS | ENSMMUP00000038190 | ENSMMUP00000022556 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | Mitochondrial antiviral-signaling protein isoform 1. | 0.974 |
IKBKE | OPTN | ENSMMUP00000038190 | ENSMMUP00000065325 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | Optineurin; Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection. Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex th [...] | 0.826 |
IKBKE | STING1 | ENSMMUP00000038190 | ENSMMUP00000015803 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | Stimulator of interferon protein. | 0.988 |
IKBKE | TANK | ENSMMUP00000038190 | ENSMMUP00000057943 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | TRAF family member-associated NF-kappa-B activator isoform a. | 0.995 |
IKBKE | TBK1 | ENSMMUP00000038190 | ENSMMUP00000010063 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | Serine/threonine-protein kinase TBK1. | 0.998 |
IKBKE | TRAF3 | ENSMMUP00000038190 | ENSMMUP00000066374 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.998 |
IKBKE | TRAF5 | ENSMMUP00000038190 | ENSMMUP00000038268 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.829 |
IKBKE | TRAF6 | ENSMMUP00000038190 | ENSMMUP00000024012 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] | 0.970 |
IRF3 | IKBKE | ENSMMUP00000029942 | ENSMMUP00000038190 | Interferon regulatory factor 3. | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | 0.931 |
IRF3 | IRF7 | ENSMMUP00000029942 | ENSMMUP00000009317 | Interferon regulatory factor 3. | Interferon regulatory factor 7. | 0.909 |
IRF3 | MAVS | ENSMMUP00000029942 | ENSMMUP00000022556 | Interferon regulatory factor 3. | Mitochondrial antiviral-signaling protein isoform 1. | 0.995 |
IRF3 | STING1 | ENSMMUP00000029942 | ENSMMUP00000015803 | Interferon regulatory factor 3. | Stimulator of interferon protein. | 0.985 |
IRF3 | TANK | ENSMMUP00000029942 | ENSMMUP00000057943 | Interferon regulatory factor 3. | TRAF family member-associated NF-kappa-B activator isoform a. | 0.872 |
IRF3 | TBK1 | ENSMMUP00000029942 | ENSMMUP00000010063 | Interferon regulatory factor 3. | Serine/threonine-protein kinase TBK1. | 0.997 |
IRF3 | TRAF3 | ENSMMUP00000029942 | ENSMMUP00000066374 | Interferon regulatory factor 3. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.919 |
IRF3 | TRAF5 | ENSMMUP00000029942 | ENSMMUP00000038268 | Interferon regulatory factor 3. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.726 |
IRF3 | TRAF6 | ENSMMUP00000029942 | ENSMMUP00000024012 | Interferon regulatory factor 3. | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] | 0.856 |
IRF7 | IKBKE | ENSMMUP00000009317 | ENSMMUP00000038190 | Interferon regulatory factor 7. | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1. | 0.961 |