Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CLCN6Chloride transport protein 6 isoform ClC-6a; Belongs to the chloride channel (TC 2.A.49) family. (869 aa)    
Predicted Functional Partners:
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
    
 0.954
CLN5
Uncharacterized protein.
      
 0.794
ARSG
Arylsulfatase G.
   
  
 0.769
SGSH
N-sulfoglucosamine sulfohydrolase.
   
  
 0.741
MFSD8
Major facilitator superfamily domain-containing protein 8.
      
 0.686
OCRL
Inositol polyphosphate 5-phosphatase OCRL-1 isoform b.
   
  
 0.677
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.673
PRPF3
Pre-mRNA processing factor 3.
      
 0.671
CHRNG
Cholinergic receptor nicotinic gamma subunit.
      
 0.669
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
  
 0.667
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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