Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AUNIPAurora kinase A and ninein interacting protein. (351 aa)    
Predicted Functional Partners:
AURKA
Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily.
   
 
 0.747
ZNF750
Zinc finger protein 750.
      
 0.579
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
   
  
 0.575
DTL
Denticleless E3 ubiquitin protein ligase homolog.
   
  
 0.554
AURKB
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 
 0.511
EIPR1
EARP complex and GARP complex interacting protein 1.
      
 0.417
ANLN
Anillin actin binding protein.
   
  
 0.414
ECT2
Epithelial cell transforming 2.
   
  
 0.412
ECM1
Extracellular matrix protein 1 isoform 1.
  
     0.401
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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