STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1437 aa)    
Predicted Functional Partners:
TFPT
TCF3 fusion partner.
    
 
 0.700
RASL10B
Ras-like protein family member 10B.
      
 0.688
RASIP1
Ras interacting protein 1.
      
 0.688
CATSPER2
Cation channel sperm-associated protein 2 isoform 4.
      
 0.649
DGKQ
Diacylglycerol kinase.
   
  
 0.649
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 
 0.639
STRC
Stereocilin.
      
 0.636
CDC26
Anaphase-promoting complex subunit CDC26.
      
 0.629
RAB33A
Small GTP-binding protein S10.
      
 0.628
EEF1B2
Elongation factor 1-beta; Belongs to the EF-1-beta/EF-1-delta family.
      
 0.588
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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