Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FBXL12F-box and leucine-rich repeat protein 12. (326 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.958
SKP1-2
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.893
ZNF846
Zinc finger protein 846.
    
 
 0.810
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.800
TBC1D21
TBC1 domain family member 21.
      
 0.767
SERINC2
Serine incorporator 2; Belongs to the peptidase C1 family.
      
 0.706
CCDC88C
Coiled-coil domain containing 88C.
      
 0.706
AKAP8L
Uncharacterized protein; Belongs to the AKAP95 family.
   
 
 0.675
FBXW8
F-box and WD repeat domain containing 8.
    
 0.668
FAT3
FAT atypical cadherin 3.
    
 
 0.628
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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