Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMOD4Tropomodulin 4. (345 aa)    
Predicted Functional Partners:
SCIN
Scinderin.
    
 
 0.844
ADD2
Beta-adducin isoform a.
    
 
 0.779
GSN
Gelsolin.
    
 
 0.726
MYBPC1
Myosin binding protein C, slow type.
   
 
 0.721
MYO18B
Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.719
MYPN
Myopalladin.
   
 
 0.713
TPM4
Tropomyosin alpha-4 chain isoform 1; Belongs to the tropomyosin family.
   
 0.710
MYLK2
Myosin light chain kinase 2.
   
  
 0.694
ACTN3
Uncharacterized protein.
   
 
 0.686
ADD1
Adducin 1.
    
 
 0.680
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (22%) [HD]