STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF4E3 ubiquitin ligase RNF4 isoform 1. (190 aa)    
Predicted Functional Partners:
CISD1
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.946
SUMO1
Small ubiquitin-related modifier.
   
 
 0.892
UBE2N
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.892
UBB
Uncharacterized protein.
    
 0.861
ENSMMUP00000072025
Small ubiquitin-related modifier.
   
 
 0.829
LOC699185
Small ubiquitin-related modifier.
   
 
 0.829
UBA52
Ubiquitin-60S ribosomal protein L40.
    
  0.806
KXD1
KxDL domain-containing protein.
    
   0.801
DAXX
Death domain associated protein.
    
 0.768
PIAS1
Protein inhibitor of activated STAT protein 1.
    
 0.757
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.