Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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FMO3Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] (532 aa)    
Predicted Functional Partners:
LOC100424965
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.957
CYP2D42
Cytochrome P450 CYP2D42; Belongs to the cytochrome P450 family.
   
 0.930
GADL1
Glutamate decarboxylase like 1.
   
 0.908
GAD2
Glutamate decarboxylase 2.
   
 0.908
CSAD
Cysteine sulfinic acid decarboxylase.
   
 0.908
GAD1
Glutamate decarboxylase 1 isoform GAD67.
   
 0.908
BAAT
Bile acid-CoA:amino acid N-acyltransferase.
   
 
  0.905
ADO
2-aminoethanethiol dioxygenase.
     
  0.900
CUTC
Copper homeostasis protein cutC homolog.
      
 0.760
GGT5
Gamma-glutamyltransferase 5.
  
 
 0.683
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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