Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHF6PHD finger protein 6 isoform 1. (365 aa)    
Predicted Functional Partners:
PLAC1
Placenta-specific protein 1.
      
 0.675
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.647
LYAR
Cell growth-regulating nucleolar protein.
   
 
 0.630
RBBP4
WD_REPEATS_REGION domain-containing protein.
   
 0.629
LOC106995979
Histone-binding protein RBBP4 isoform a.
   
 0.629
LOC697938
WD_REPEATS_REGION domain-containing protein.
   
 0.629
FAM126B
Uncharacterized protein.
      
 0.612
ASXL1
ASXL transcriptional regulator 1.
   
 0.608
KDM6A
Lysine demethylase 6A.
   
 0.594
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.591
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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