Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC8CLeucine-rich repeat-containing protein 8C. (803 aa)    
Predicted Functional Partners:
LRRC8A
Leucine-rich repeat-containing protein 8A.
   
 0.978
LRRC8B
Leucine-rich repeat-containing protein 8B.
    
 0.840
TTYH1
Protein tweety homolog; Probable chloride channel.
      
 0.700
TTYH2
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.621
TTYH3
Protein tweety homolog; Probable chloride channel.
      
 0.533
LRRC8D
Leucine-rich repeat-containing protein 8D.
   
  0.522
CORIN
Corin, serine peptidase.
   
 0.517
KERA
Keratocan.
  
     0.462
LRFN5
Leucine rich repeat and fibronectin type III domain containing 5.
  
     0.461
LRRC26
Leucine rich repeat containing 26.
  
   
 0.458
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.