Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPR1Guanylate cyclase. (1061 aa)    
Predicted Functional Partners:
NPPA
Natriuretic peptide A.
    
 0.997
NPPB
Natriuretic peptide B.
    
 0.986
NPPC
C-type natriuretic peptide.
    
 0.950
LOC694289
Uncharacterized protein.
    
 0.926
VIP
VIP peptides isoform 1 preproprotein.
     
 0.917
NPR2
Guanylate cyclase.
  
 
0.906
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.906
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.906
GCG
Glucagon.
   
 
 0.905
CRH
Corticotropin releasing hormone.
     
 0.902
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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