Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF3Immunoglobulin superfamily member 3. (1215 aa)    
Predicted Functional Partners:
PDZRN3
PDZ domain containing ring finger 3.
    
 
 0.722
RABGEF1
Uncharacterized protein.
    
 0.690
LOC114670534
Ig-like domain-containing protein.
      
 0.668
ENSMMUP00000078957
Ig-like domain-containing protein.
      
 0.668
PRAME
Preferentially expressed antigen in melanoma.
      
 0.663
CDR2
Cerebellar degeneration-related protein 2.
    
   0.657
TIAM2
T cell lymphoma invasion and metastasis 2.
    
 
 0.631
CROCC
Ciliary rootlet coiled-coil, rootletin.
      
 0.602
GGT5
Gamma-glutamyltransferase 5.
      
 0.583
FLRT3
Fibronectin-like domain-containing leucine-rich transmembrane protein 3.
    
 0.554
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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