Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (336 aa)    
Predicted Functional Partners:
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.998
MCU
Mitochondrial calcium uniporter.
  
 
0.997
MICU2
Mitochondrial calcium uptake 2.
    
 0.997
MICU1
Uncharacterized protein.
    
 0.988
MICU3
Mitochondrial calcium uptake family member 3.
    
 0.985
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
    
   0.744
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.638
MCUR1
Mitochondrial calcium uniporter regulator 1.
    
 
 0.600
PHB
Prohibitin.
     
 0.537
MAIP1
Uncharacterized protein.
     
 0.537
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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