Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FEM1BProtein fem-1 homolog B. (627 aa)    
Predicted Functional Partners:
CUL2
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.953
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.926
COPS6
COP9 signalosome subunit 6.
    
 0.910
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.896
COPS3
COP9 signalosome complex subunit 3 isoform 1.
    
 0.848
ELOB
Transcription elongation factor B polypeptide 2 isoform a.
    
 0.845
COPS5
COP9 signalosome complex subunit 5.
   
 0.820
COPS2
COP9 signalosome complex subunit 2 isoform 1.
    
  0.812
LOC699342
PCI domain-containing protein.
    
  0.812
COPS8
COP9 signalosome subunit 8.
    
 0.793
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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