Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTSWCathepsin W; Belongs to the peptidase C1 family. (375 aa)    
Predicted Functional Partners:
NKG7
Natural killer cell granule protein 7.
   
  
 0.913
BID
BH3 interacting domain death agonist.
   
 
  0.901
BCL2L1
Bcl-2-like protein 1 isoform 1.
     
  0.900
BCL2
BCL2 apoptosis regulator.
     
  0.900
PRF1
Perforin 1.
   
 
 0.873
GNLY
Uncharacterized protein.
   
 
 0.806
GZMA
Granzyme A; Belongs to the peptidase S1 family.
   
 
 0.770
CD96
CD96 molecule.
   
    0.755
CD3E
CD3e molecule.
   
  
 0.736
KLRD1
Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
   
 
 0.707
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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