Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ANKRD52Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C. (1076 aa)    
Predicted Functional Partners:
PPP6R2
Protein phosphatase 6 regulatory subunit 2.
    
 0.953
PPP6R3
Protein phosphatase 6 regulatory subunit 3.
    
 0.875
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
    
 0.866
PPP6C
Serine/threonine-protein phosphatase.
    
 0.838
PAIP2
Polyadenylate-binding protein-interacting protein 2.
      
 0.767
LOC114675532
Serine/threonine-protein phosphatase.
    
 0.764
ANKRD28
Ankyrin repeat domain 28.
    
 0.745
FAM98A
Uncharacterized protein.
      
 0.720
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.715
EIF3J
Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
   
 
 0.696
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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