Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (335 aa)    
Predicted Functional Partners:
CCND3
Cyclin D3; Belongs to the cyclin family.
   
 0.999
CCND1
Uncharacterized protein; Belongs to the cyclin family.
   
 0.999
CDKN2B
Cyclin dependent kinase inhibitor 2B.
    
 0.998
RB1
Retinoblastoma-associated protein.
   
 0.998
CDKN2C
Cyclin-dependent kinase 4 inhibitor C.
   
 0.997
CDKN1A
Cyclin-dependent kinase inhibitor 1.
   
 0.997
CDKN2D
Cyclin-dependent kinase 4 inhibitor D.
    
 0.996
CCNE1
Cyclin E1; Belongs to the cyclin family.
   
 0.996
CDK4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
  
 
0.996
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
   
 0.996
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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