TRHR protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNA11	GNA14	ENSMMUP00000003957	ENSMMUP00000022417	Guanine nucleotide-binding protein subunit alpha-11.	G protein subunit alpha 14.	0.900
GNA11	GNAQ	ENSMMUP00000003957	ENSMMUP00000061851	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.965
GNA11	GNB1	ENSMMUP00000003957	ENSMMUP00000066781	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.977
GNA11	GNB2	ENSMMUP00000003957	ENSMMUP00000071351	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.972
GNA11	GNB3	ENSMMUP00000003957	ENSMMUP00000006868	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.967
GNA11	GNB4	ENSMMUP00000003957	ENSMMUP00000005459	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein subunit beta-4.	0.977
GNA11	GNB5	ENSMMUP00000003957	ENSMMUP00000022869	Guanine nucleotide-binding protein subunit alpha-11.	G protein subunit beta 5.	0.964
GNA11	GNG4	ENSMMUP00000003957	ENSMMUP00000064430	Guanine nucleotide-binding protein subunit alpha-11.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.971
GNA11	TRHR	ENSMMUP00000003957	ENSMMUP00000011445	Guanine nucleotide-binding protein subunit alpha-11.	Thyrotropin-releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family.	0.941
GNA14	GNA11	ENSMMUP00000022417	ENSMMUP00000003957	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit alpha-11.	0.900
GNA14	GNAQ	ENSMMUP00000022417	ENSMMUP00000061851	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(Q) subunit alpha.	0.965
GNA14	GNB1	ENSMMUP00000022417	ENSMMUP00000066781	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.977
GNA14	GNB2	ENSMMUP00000022417	ENSMMUP00000071351	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.972
GNA14	GNB3	ENSMMUP00000022417	ENSMMUP00000006868	G protein subunit alpha 14.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.967
GNA14	GNB4	ENSMMUP00000022417	ENSMMUP00000005459	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit beta-4.	0.977
GNA14	GNB5	ENSMMUP00000022417	ENSMMUP00000022869	G protein subunit alpha 14.	G protein subunit beta 5.	0.980
GNA14	GNG4	ENSMMUP00000022417	ENSMMUP00000064430	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.971
GNA14	TRHR	ENSMMUP00000022417	ENSMMUP00000011445	G protein subunit alpha 14.	Thyrotropin-releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family.	0.941
GNAQ	GNA11	ENSMMUP00000061851	ENSMMUP00000003957	Guanine nucleotide-binding protein G(Q) subunit alpha.	Guanine nucleotide-binding protein subunit alpha-11.	0.965
GNAQ	GNA14	ENSMMUP00000061851	ENSMMUP00000022417	Guanine nucleotide-binding protein G(Q) subunit alpha.	G protein subunit alpha 14.	0.965