Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PCBD1Pterin-4-alpha-carbinolamine dehydratase. (104 aa)    
Predicted Functional Partners:
PAH
Phenylalanine hydroxylase.
  
 0.978
TPH1
Tryptophan hydroxylase 1.
  
 0.975
TH
Tyrosine hydroxylase.
  
 0.974
TPH2
Tryptophan 5-hydroxylase 2.
  
 0.974
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 
0.972
HNF1A
HNF1 homeobox A.
    
 
 0.858
QDPR
Quinoid dihydropteridine reductase.
   
 
 0.828
HNF1B
Hepatocyte nuclear factor 1-beta.
    
 
 0.780
AFMID
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
    
 
 0.759
UAP1L1
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1.
   
   0.752
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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