Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)    
Predicted Functional Partners:
PKD1
Polycystin 1, transient receptor potential channel interacting.
   
0.993
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.820
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.812
IFT20
Intraflagellar transport protein 20-like protein.
   
  
 0.763
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
     
  0.735
EXOC5
Exocyst complex component 5.
     
 0.688
RHO
Rhodopsin.
     
 0.680
EXOC4
Exocyst complex component 4 isoform a.
     
 0.675
PKDREJ
Polycystin family receptor for egg jelly.
   
 0.657
IFT140
Intraflagellar transport 140.
      
 0.634
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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