Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DEFB119Macaca mulatta defensin, beta 119 (DEFB119), mRNA. (88 aa)    
Predicted Functional Partners:
DEFB121
Beta-defensin 121; Has antibacterial activity.
   
 
 0.858
DEFB123
Beta-defensin 123; Has antibacterial activity.
   
 
 0.811
DEFB122
Beta-defensin 122; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.801
DEFB1
Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
     
 0.798
DEFB129
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.771
DEFB136
Defensin, beta 136.
     
 0.770
EDDM3B
Ribonuclease A M1.
      
 0.767
WFDC9
WAP four-disulfide core domain 9.
      
 0.767
EDDM3A
Epididymal protein 3A.
      
 0.767
WFDC11
Uncharacterized protein.
      
 0.767
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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