Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ARL8BADP-ribosylation factor-like protein 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)    
Predicted Functional Partners:
PLEKHM2
Pleckstrin homology domain-containing family M member 2.
   
 0.959
PLEKHM1
Pleckstrin homology and RUN domain containing M1.
    
 
 0.815
RAB7A
RAB7A, member RAS oncogene family.
   
 0.721
SLC66A1
Solute carrier family 66 member 1.
    
 
 0.688
VPS39
Uncharacterized protein.
    
 
 0.685
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.651
LAMP1
Lysosomal associated membrane protein 1.
    
 0.631
PIP4P1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
   
 
 0.616
PCDHGB5
Protocadherin gamma subfamily B, 5.
    
 0.614
RAB2A
Uncharacterized protein.
   
 
 0.613
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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