Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (555 aa)    
Predicted Functional Partners:
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.813
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1.
    
 
 0.660
GSAP
Gamma-secretase activating protein.
   
 
 0.649
CALN1
Calneuron 1.
      
 0.630
SQSTM1
Sequestosome 1.
   
 
 0.600
NBR1
NBR1 autophagy cargo receptor.
   
 
 0.600
HECTD2
HECT domain E3 ubiquitin protein ligase 2.
    
 
 0.593
EPN2
Epsin-2 isoform b.
    
 
 0.567
ENTHD1
ENTH domain containing 1.
    
 
 0.567
EPN3
Epsin 3.
    
 
 0.567
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.