HDAC2 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	CHD4	ENSMMUP00000057619	ENSMMUP00000024592	Uncharacterized protein.	Chromodomain helicase DNA binding protein 4.	0.999
CHD3	GATAD2B	ENSMMUP00000057619	ENSMMUP00000049540	Uncharacterized protein.	GATA zinc finger domain containing 2B.	0.996
CHD3	HDAC1	ENSMMUP00000057619	ENSMMUP00000013015	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.996
CHD3	HDAC2	ENSMMUP00000057619	ENSMMUP00000057724	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.995
CHD3	MTA1	ENSMMUP00000057619	ENSMMUP00000022782	Uncharacterized protein.	Metastasis associated 1.	0.996
CHD3	RBBP4	ENSMMUP00000057619	ENSMMUP00000013002	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.985
CHD3	RCOR1	ENSMMUP00000057619	ENSMMUP00000055756	Uncharacterized protein.	REST corepressor 1.	0.643
CHD3	SAP30	ENSMMUP00000057619	ENSMMUP00000003221	Uncharacterized protein.	Histone deacetylase complex subunit SAP30.	0.611
CHD3	SIN3A	ENSMMUP00000057619	ENSMMUP00000012162	Uncharacterized protein.	SIN3 transcription regulator family member A.	0.608
CHD4	CHD3	ENSMMUP00000024592	ENSMMUP00000057619	Chromodomain helicase DNA binding protein 4.	Uncharacterized protein.	0.999
CHD4	GATAD2B	ENSMMUP00000024592	ENSMMUP00000049540	Chromodomain helicase DNA binding protein 4.	GATA zinc finger domain containing 2B.	0.996
CHD4	HDAC1	ENSMMUP00000024592	ENSMMUP00000013015	Chromodomain helicase DNA binding protein 4.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.997
CHD4	HDAC2	ENSMMUP00000024592	ENSMMUP00000057724	Chromodomain helicase DNA binding protein 4.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.996
CHD4	MTA1	ENSMMUP00000024592	ENSMMUP00000022782	Chromodomain helicase DNA binding protein 4.	Metastasis associated 1.	0.997
CHD4	RBBP4	ENSMMUP00000024592	ENSMMUP00000013002	Chromodomain helicase DNA binding protein 4.	WD_REPEATS_REGION domain-containing protein.	0.989
CHD4	RCOR1	ENSMMUP00000024592	ENSMMUP00000055756	Chromodomain helicase DNA binding protein 4.	REST corepressor 1.	0.655
CHD4	SAP30	ENSMMUP00000024592	ENSMMUP00000003221	Chromodomain helicase DNA binding protein 4.	Histone deacetylase complex subunit SAP30.	0.628
CHD4	SIN3A	ENSMMUP00000024592	ENSMMUP00000012162	Chromodomain helicase DNA binding protein 4.	SIN3 transcription regulator family member A.	0.690
CTBP1	GATAD2B	ENSMMUP00000079312	ENSMMUP00000049540	C-terminal-binding protein 1 isoform 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	GATA zinc finger domain containing 2B.	0.462
CTBP1	HDAC1	ENSMMUP00000079312	ENSMMUP00000013015	C-terminal-binding protein 1 isoform 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.992