Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAX2Paired box 2. (418 aa)    
Predicted Functional Partners:
PAX5
Paired box 5.
   
   0.907
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 0.872
SIX1
SIX homeobox 1.
   
 0.869
GATA3
GATA binding protein 3.
     
 0.830
WT1
WT1 transcription factor.
    
 0.814
SIX2
SIX homeobox 2.
    
 0.794
LHX1
LIM homeobox 1.
   
 0.786
EMX2
Homeobox protein EMX2 isoform 1.
    
 0.775
LMX1B
LIM homeobox transcription factor 1-beta isoform 1.
   
 0.752
POU2AF1
POU class 2 homeobox associating factor 1.
   
 
 0.750
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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