Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CUEDC1CUE domain-containing protein 1. (388 aa)    
Predicted Functional Partners:
ARRDC3
TBP-2-like inducible membrane protein.
    
   0.723
TOM1L2
Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family.
    
   0.717
LDLRAD4
Uncharacterized protein.
    
   0.651
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2.
    
   0.624
ITCH
E3 ubiquitin-protein ligase.
    
   0.587
ARRDC1
Arrestin domain-containing protein 1.
    
   0.545
EIF3D
Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]
      
 0.526
ZFPM2
Zinc finger protein, FOG family member 2.
    
 
 0.520
HSPH1
Uncharacterized protein.
      
 0.499
ARRDC4
Arrestin domain containing 4.
    
   0.496
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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