IL18R1 protein (Macaca mulatta) - STRING interaction network

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Score

IL18R1

Interleukin 18 receptor 1. (540 aa)

Predicted Functional Partners:

IL18RAP

0.997

IL18

0.997

IL37

0.987

IL33

0.802

IL18BP

0.738

ZPBP

0.711

HESX1

0.667

STAT3

0.600

RABEP2

0.592

SGF29

0.578

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HESX1	IL18R1	ENSMMUP00000055160	ENSMMUP00000012112	HESX homeobox 1.	Interleukin 18 receptor 1.	0.667
HESX1	ZPBP	ENSMMUP00000055160	ENSMMUP00000061488	HESX homeobox 1.	Zona pellucida binding protein.	0.733
IL18	IL18BP	ENSMMUP00000078058	ENSMMUP00000077445	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin 18 binding protein.	0.948
IL18	IL18R1	ENSMMUP00000078058	ENSMMUP00000012112	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin 18 receptor 1.	0.997
IL18	IL18RAP	ENSMMUP00000078058	ENSMMUP00000036207	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin 18 receptor accessory protein.	0.992
IL18	IL33	ENSMMUP00000078058	ENSMMUP00000028116	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-33 isoform 1.	0.808
IL18	IL37	ENSMMUP00000078058	ENSMMUP00000007789	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1.	0.962
IL18	STAT3	ENSMMUP00000078058	ENSMMUP00000043986	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Signal transducer and activator of transcription.	0.698
IL18BP	IL18	ENSMMUP00000077445	ENSMMUP00000078058	Interleukin 18 binding protein.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.948
IL18BP	IL18R1	ENSMMUP00000077445	ENSMMUP00000012112	Interleukin 18 binding protein.	Interleukin 18 receptor 1.	0.738
IL18BP	IL18RAP	ENSMMUP00000077445	ENSMMUP00000036207	Interleukin 18 binding protein.	Interleukin 18 receptor accessory protein.	0.591
IL18BP	IL37	ENSMMUP00000077445	ENSMMUP00000007789	Interleukin 18 binding protein.	Interleukin-1.	0.871
IL18R1	HESX1	ENSMMUP00000012112	ENSMMUP00000055160	Interleukin 18 receptor 1.	HESX homeobox 1.	0.667
IL18R1	IL18	ENSMMUP00000012112	ENSMMUP00000078058	Interleukin 18 receptor 1.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.997
IL18R1	IL18BP	ENSMMUP00000012112	ENSMMUP00000077445	Interleukin 18 receptor 1.	Interleukin 18 binding protein.	0.738
IL18R1	IL18RAP	ENSMMUP00000012112	ENSMMUP00000036207	Interleukin 18 receptor 1.	Interleukin 18 receptor accessory protein.	0.997
IL18R1	IL33	ENSMMUP00000012112	ENSMMUP00000028116	Interleukin 18 receptor 1.	Interleukin-33 isoform 1.	0.802
IL18R1	IL37	ENSMMUP00000012112	ENSMMUP00000007789	Interleukin 18 receptor 1.	Interleukin-1.	0.987
IL18R1	RABEP2	ENSMMUP00000012112	ENSMMUP00000030968	Interleukin 18 receptor 1.	Rabaptin, RAB GTPase binding effector protein 2.	0.592
IL18R1	SGF29	ENSMMUP00000012112	ENSMMUP00000068257	Interleukin 18 receptor 1.	SGF29 C-terminal domain-containing protein.	0.578