Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C5AR2Complement component 5a receptor 2. (337 aa)    
Predicted Functional Partners:
C5
Complement C5.
    
 0.986
C3
Uncharacterized protein.
    
 0.780
LOC714514
Uncharacterized protein.
    
 0.737
LOC723314
Uncharacterized protein.
    
 0.663
LOC721200
Uncharacterized protein.
    
 0.663
CD46
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
     
 0.507
CFP
Complement factor properdin.
   
  
 0.486
LAMTOR5
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.
      
 0.484
TNFSF8
Tumor necrosis factor ligand superfamily member 8; Belongs to the tumor necrosis factor family.
   
  
 0.477
ZNF518A
Zinc finger protein 518A.
  
 
  0.462
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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