PKNOX1 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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Co-expression

Experiments

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[Homology]

Score

PKNOX1

PBX/knotted 1 homeobox 1. (503 aa)

Predicted Functional Partners:

PBX1

0.979

PBX2

0.955

PBX4

0.906

HOXB1

0.847

PBX3

0.757

SHOX

0.713

VWA5A

0.708

HMGB2

0.619

HMGB4

0.619

HOXB2

0.547

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HMGB2	PKNOX1	ENSMMUP00000004251	ENSMMUP00000012167	High mobility group protein B2.	PBX/knotted 1 homeobox 1.	0.619
HMGB4	PKNOX1	ENSMMUP00000040436	ENSMMUP00000012167	High mobility group box 4.	PBX/knotted 1 homeobox 1.	0.619
HOXB1	HOXB2	ENSMMUP00000029241	ENSMMUP00000071744	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Homeobox B2.	0.453
HOXB1	PBX1	ENSMMUP00000029241	ENSMMUP00000014901	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Pre-B-cell leukemia transcription factor 1 isoform 1.	0.933
HOXB1	PBX2	ENSMMUP00000029241	ENSMMUP00000018094	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Pre-B-cell leukemia transcription factor 2.	0.744
HOXB1	PBX3	ENSMMUP00000029241	ENSMMUP00000018097	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Pre-B-cell leukemia transcription factor 3 isoform 1.	0.743
HOXB1	PBX4	ENSMMUP00000029241	ENSMMUP00000054807	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	PBX homeobox 4.	0.861
HOXB1	PKNOX1	ENSMMUP00000029241	ENSMMUP00000012167	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	PBX/knotted 1 homeobox 1.	0.847
HOXB2	HOXB1	ENSMMUP00000071744	ENSMMUP00000029241	Homeobox B2.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.453
HOXB2	PBX1	ENSMMUP00000071744	ENSMMUP00000014901	Homeobox B2.	Pre-B-cell leukemia transcription factor 1 isoform 1.	0.594
HOXB2	PKNOX1	ENSMMUP00000071744	ENSMMUP00000012167	Homeobox B2.	PBX/knotted 1 homeobox 1.	0.547
PBX1	HOXB1	ENSMMUP00000014901	ENSMMUP00000029241	Pre-B-cell leukemia transcription factor 1 isoform 1.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.933
PBX1	HOXB2	ENSMMUP00000014901	ENSMMUP00000071744	Pre-B-cell leukemia transcription factor 1 isoform 1.	Homeobox B2.	0.594
PBX1	PBX2	ENSMMUP00000014901	ENSMMUP00000018094	Pre-B-cell leukemia transcription factor 1 isoform 1.	Pre-B-cell leukemia transcription factor 2.	0.907
PBX1	PBX3	ENSMMUP00000014901	ENSMMUP00000018097	Pre-B-cell leukemia transcription factor 1 isoform 1.	Pre-B-cell leukemia transcription factor 3 isoform 1.	0.906
PBX1	PKNOX1	ENSMMUP00000014901	ENSMMUP00000012167	Pre-B-cell leukemia transcription factor 1 isoform 1.	PBX/knotted 1 homeobox 1.	0.979
PBX1	SHOX	ENSMMUP00000014901	ENSMMUP00000025020	Pre-B-cell leukemia transcription factor 1 isoform 1.	Short stature homeobox.	0.499
PBX2	HOXB1	ENSMMUP00000018094	ENSMMUP00000029241	Pre-B-cell leukemia transcription factor 2.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.744
PBX2	PBX1	ENSMMUP00000018094	ENSMMUP00000014901	Pre-B-cell leukemia transcription factor 2.	Pre-B-cell leukemia transcription factor 1 isoform 1.	0.907
PBX2	PBX3	ENSMMUP00000018094	ENSMMUP00000018097	Pre-B-cell leukemia transcription factor 2.	Pre-B-cell leukemia transcription factor 3 isoform 1.	0.710