Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMC1AStructural maintenance of chromosomes protein. (1233 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
  
0.999
STAG2
Cohesin subunit SA-2 isoform a.
   
 0.999
RAD21
Double-strand-break repair protein rad21 homolog.
   
 0.999
STAG1
Cohesin subunit SA-1.
   
 0.998
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.996
PDS5B
Sister chromatid cohesion protein PDS5 homolog B.
   
 0.990
REC8
REC8 meiotic recombination protein.
   
 0.990
PDS5A
Sister chromatid cohesion protein PDS5 homolog A isoform 1.
   
 0.990
WAPL
WAPL cohesin release factor.
   
 0.987
NIPBL
Nipped-B protein.
   
 0.984
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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