Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM2ADAM metallopeptidase domain 2. (735 aa)    
Predicted Functional Partners:
CLGN
Calmegin.
   
 
 0.858
OVGP1
Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.
   
 
 0.710
EEF2
Elongation factor 2.
   
   0.699
CYP3A43
Uncharacterized protein.
   
  
 0.672
CCDC54
Coiled-coil domain containing 54.
   
  
 0.667
PYDC2
PYRIN-only protein 2.
   
  
 0.637
SYBU
Syntabulin isoform a.
      
 0.632
IZUMO3
IZUMO family member 3.
   
  
 0.607
RMDN2
Regulator of microtubule dynamics 2.
    
 0.605
CATSPER1
Cation channel sperm associated 1.
   
  
 0.600
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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