ICAM1 protein (Macaca mulatta) - STRING interaction network

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ICAM1

Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (543 aa)

Predicted Functional Partners:

ITGAL

0.996

ITGB2

0.989

ITGAM

0.986

EZR

0.977

ICAM2

0.974

VCAM1

0.967

MSN

0.960

CD80

0.959

PLCG2

0.917

KRAS

0.915

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD80	ICAM1	ENSMMUP00000074900	ENSMMUP00000012236	CD80 molecule.	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	0.959
CD80	ITGAL	ENSMMUP00000074900	ENSMMUP00000032459	CD80 molecule.	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	0.457
CD80	ITGAM	ENSMMUP00000074900	ENSMMUP00000052151	CD80 molecule.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.565
CD80	ITGB2	ENSMMUP00000074900	ENSMMUP00000073991	CD80 molecule.	Integrin beta.	0.483
CD80	VCAM1	ENSMMUP00000074900	ENSMMUP00000030169	CD80 molecule.	Vascular cell adhesion molecule 1.	0.424
EZR	ICAM1	ENSMMUP00000025573	ENSMMUP00000012236	Ezrin.	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	0.977
EZR	ICAM2	ENSMMUP00000025573	ENSMMUP00000019231	Ezrin.	ICAM_N domain-containing protein.	0.759
EZR	MSN	ENSMMUP00000025573	ENSMMUP00000070350	Ezrin.	FERM domain-containing protein.	0.995
EZR	VCAM1	ENSMMUP00000025573	ENSMMUP00000030169	Ezrin.	Vascular cell adhesion molecule 1.	0.939
ICAM1	CD80	ENSMMUP00000012236	ENSMMUP00000074900	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	CD80 molecule.	0.959
ICAM1	EZR	ENSMMUP00000012236	ENSMMUP00000025573	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	Ezrin.	0.977
ICAM1	ICAM2	ENSMMUP00000012236	ENSMMUP00000019231	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	ICAM_N domain-containing protein.	0.974
ICAM1	ITGAL	ENSMMUP00000012236	ENSMMUP00000032459	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	0.996
ICAM1	ITGAM	ENSMMUP00000012236	ENSMMUP00000052151	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.986
ICAM1	ITGB2	ENSMMUP00000012236	ENSMMUP00000073991	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	Integrin beta.	0.989
ICAM1	KRAS	ENSMMUP00000012236	ENSMMUP00000002635	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	KRAS proto-oncogene, GTPase.	0.915
ICAM1	MSN	ENSMMUP00000012236	ENSMMUP00000070350	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	FERM domain-containing protein.	0.960
ICAM1	PLCG2	ENSMMUP00000012236	ENSMMUP00000007058	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.917
ICAM1	VCAM1	ENSMMUP00000012236	ENSMMUP00000030169	Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.	Vascular cell adhesion molecule 1.	0.967
ICAM2	EZR	ENSMMUP00000019231	ENSMMUP00000025573	ICAM_N domain-containing protein.	Ezrin.	0.759

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