Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MEGF6Multiple EGF like domains 6. (1541 aa)    
Predicted Functional Partners:
HMGXB4
HMG-box containing 4.
      
 0.534
LTN1
Listerin E3 ubiquitin protein ligase 1.
      
 0.533
ZBTB40
Zinc finger and BTB domain containing 40.
    
 0.530
RITA1
RBPJ interacting and tubulin associated 1.
      
 0.530
CTNNAL1
Catenin alpha like 1.
    
 0.501
LOC114669846
ANAPC4_WD40 domain-containing protein.
    
 
 0.499
WRAP73
WD repeat containing, antisense to TP73.
    
 
 0.499
UBOX5
Ubiquitin-conjugating enzyme 7-interacting protein 5.
    
 
 0.435
ARHGEF25
Rho guanine nucleotide exchange factor 25.
   
 0.421
FBLIM1
Filamin binding LIM protein 1.
    
 
 0.409
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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