close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFAP2CTranscription factor AP-2 gamma. (450 aa)    
Predicted Functional Partners:
PRDM14
PR domain-containing protein 14.
    
 
 0.846
WWOX
WW domain containing oxidoreductase.
    
 0.831
SOX17
SRY-box transcription factor 17.
   
  
 0.782
NANOS3
Nanos C2HC-type zinc finger 3; Belongs to the nanos family.
   
  
 0.745
KDM5B
Lysine demethylase 5B.
   
 0.739
KCTD1
Potassium channel tetramerization domain containing 1.
   
 0.732
ZIC2
Zic family member 2.
    
 
 0.732
ZIC1
Zic family member 1.
    
 
 0.716
GATA3
GATA binding protein 3.
   
 
 0.701
KRT7
Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family.
   
  
 0.685
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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