Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TFAP2CTranscription factor AP-2 gamma. (450 aa)    
Predicted Functional Partners:
TFAP2A
Transcription factor AP-2 alpha.
   
 0.962
SOX17
SRY-box transcription factor 17.
   
 0.951
WWOX
WW domain containing oxidoreductase.
    
 0.943
PRDM1
PR/SET domain 1.
     
 0.919
PRDM14
PR domain-containing protein 14.
    
 0.866
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.
    
 0.847
NANOS3
Nanos C2HC-type zinc finger 3; Belongs to the nanos family.
   
 0.844
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2.
     
 0.828
BMP4
Bone morphogenetic protein 4.
   
 
 0.809
KCTD1
Potassium channel tetramerization domain containing 1.
   
 0.795
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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