Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTMR10Myotubularin related protein 10. (775 aa)    
Predicted Functional Partners:
MTMR2
Myotubularin-related protein 2 isoform 1.
   
 0.819
FAN1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
      
 0.668
TRPM1
Transient receptor potential cation channel subfamily M member 1.
      
 0.653
MTM1
Myotubularin.
   
 0.652
MTMR1
Myotubularin related protein 1.
   
 0.645
IER3IP1
Immediate early response 3-interacting protein 1.
      
 0.579
CHRNA7
Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity).
      
 0.511
OTUD7A
OTU deubiquitinase 7A.
    
 
 0.508
UTS2B
Urotensin 2B.
      
 0.496
FREM3
FRAS1 related extracellular matrix 3.
      
 0.494
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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