STRINGSTRING
TFPI protein (Macaca mulatta) - STRING interaction network
"TFPI" - Tissue factor pathway inhibitor in Macaca mulatta
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFPITissue factor pathway inhibitor ; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma (304 aa)    
Predicted Functional Partners:
ACE2
Uncharacterized protein (797 aa)
     
   
  0.990
EGK_08858
Uncharacterized protein (1223 aa)
     
   
  0.990
F7
Coagulation factor VII (serum prothrombin conversion accelerator) (462 aa)
     
  0.969
F10
Coagulation factor X precursor (487 aa)
     
  0.956
FBN1
Fibrillin-1; Uncharacterized protein (2871 aa)
     
   
  0.885
F3
Uncharacterized protein (70 aa)
     
 
  0.834
F12
Uncharacterized protein (615 aa)
     
  0.761
HGFAC
Uncharacterized protein (651 aa)
     
  0.758
F2
Prothrombin precursor (550 aa)
     
  0.755
CPA4
Uncharacterized protein (421 aa)
     
 
  0.751
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: Cercopithecidae, Cercopithecinae, Cercopithecoidea, M. mulatta, Macaca, Macaca mulatta, Old World monkeys, Rhesus monkey, macaques, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (10%) [HD]