STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFPITissue factor pathway inhibitor; Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. (304 aa)    
Predicted Functional Partners:
F7
Coagulation factor VII.
    
 0.982
F10
Coagulation factor X.
    
 0.980
THBD
Uncharacterized protein.
   
 
 0.934
F3
Tissue factor isoform 1.
   
 
 0.742
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
    
 0.725
VWF
Uncharacterized protein.
   
  
 0.712
ENSMMUP00000072097
Ig-like domain-containing protein.
    
  0.712
F7HL06_MACMU
Uncharacterized protein.
    
  0.709
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
    
 0.709
SERPINC1
Antithrombin III; Belongs to the serpin family.
   
 
 0.704
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.