STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR15G-protein coupled receptor 15; Probable chemokine receptor. SIV-1 coreceptor; Belongs to the G-protein coupled receptor 1 family. (360 aa)    
Predicted Functional Partners:
ZNF266
Zinc finger protein 266.
      
 0.780
GSN
Gelsolin.
      
 0.688
AK5
Adenylate kinase 5; Belongs to the adenylate kinase family.
      
 0.687
FMN1
Formin 1.
      
 0.651
FADS2
Fatty acid desaturase 2.
      
 0.651
JDP2
Jun dimerization protein 2.
      
 0.651
CLDND1
Uncharacterized protein.
      
 0.633
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
   
  
 0.544
EXOC3
Exocyst complex component 3.
      
 0.540
LOC719235
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
      
 0.513
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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