Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)    
Predicted Functional Partners:
MPO
Myeloperoxidase.
   
 0.995
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
  
0.992
AZU1
Azurocidin 1.
   
 
  0.963
SERPINA1
SERPIN domain-containing protein; Belongs to the serpin family.
    
 0.941
PRTN3
Proteinase 3; Belongs to the peptidase S1 family.
  
 
0.935
RTD1A
Rhesus theta defensin-1/3 subunit A; RTD-1 and RTD-3 have similar antimicrobial activities against the Gram-positive bacteria S.aureus 502A and L.monocytogenes, the Gram- negative bacteria S.typhimurium and E.coli ML35, and the fungi C.albicans 16820 and C.neoformans 271A; Belongs to the alpha-defensin family. Theta subfamily.
   
 0.929
RTD1B
Rhesus theta defensin-1/2 subunit B; RTD-1 and RTD-2 have similar antimicrobial activities against the Gram-positive bacteria S.aureus 502A and L.monocytogenes, the Gram- negative bacterium S.typhimurium, and the fungi C.albicans 16820 and C.neoformans 271A. RTD-2 is 2-3-fold less active than RTD-1 against E.coli ML35; Belongs to the alpha-defensin family. Theta subfamily.
   
 0.927
SLPI
Uncharacterized protein.
    
 0.899
CD177
CD177 molecule.
   
 0.881
GZMB
Granzyme B; Belongs to the peptidase S1 family.
  
0.878
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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