Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CFDComplement factor D; Belongs to the peptidase S1 family. (260 aa)    
Predicted Functional Partners:
C2
Uncharacterized protein; Belongs to the peptidase S1 family.
   
0.983
C3
Uncharacterized protein.
   
 0.978
ADIPOQ
Adiponectin, C1Q and collagen domain containing.
   
  
 0.976
RETN
Uncharacterized protein.
   
 
 0.759
GZMM
Granzyme M; Belongs to the peptidase S1 family.
   
 
 0.756
DCN
Decorin; May affect the rate of fibrils formation.
   
 0.750
LOC714514
Uncharacterized protein.
   
 0.726
CFP
Complement factor properdin.
   
 0.686
SPINK5
Serine peptidase inhibitor, Kazal type 5.
    
 0.646
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 0.601
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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