CCL13 protein (Macaca mulatta) - STRING interaction network

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[Homology]

Score

CCL13

C-C motif chemokine. (98 aa)

Predicted Functional Partners:

CCL8

0.992

CCL24

0.968

CCR2

0.966

CCR1

0.964

CXCL10

0.961

CXCL11

0.961

CCR3

0.958

CCL27

0.958

CXCL9

0.958

CXCL12

0.957

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL13	CCL24	ENSMMUP00000012809	ENSMMUP00000062518	C-C motif chemokine.	Uncharacterized protein.	0.968
CCL13	CCL27	ENSMMUP00000012809	ENSMMUP00000027364	C-C motif chemokine.	Small-inducible cytokine A27.	0.958
CCL13	CCL8	ENSMMUP00000012809	ENSMMUP00000012808	C-C motif chemokine.	C-C motif chemokine.	0.992
CCL13	CCR1	ENSMMUP00000012809	ENSMMUP00000072210	C-C motif chemokine.	C-C chemokine receptor type 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.	0.964
CCL13	CCR2	ENSMMUP00000012809	ENSMMUP00000070568	C-C motif chemokine.	C-C chemokine receptor type 2; Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (By similarity). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity) Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B (By similarity). Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation (By similari [...]	0.966
CCL13	CCR3	ENSMMUP00000012809	ENSMMUP00000006084	C-C motif chemokine.	C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.	0.958
CCL13	CXCL10	ENSMMUP00000012809	ENSMMUP00000027500	C-C motif chemokine.	C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family.	0.961
CCL13	CXCL11	ENSMMUP00000012809	ENSMMUP00000066782	C-C motif chemokine.	C-X-C motif chemokine.	0.961
CCL13	CXCL12	ENSMMUP00000012809	ENSMMUP00000035953	C-C motif chemokine.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.957
CCL13	CXCL9	ENSMMUP00000012809	ENSMMUP00000045039	C-C motif chemokine.	C-X-C motif chemokine ligand 9.	0.958
CCL24	CCL13	ENSMMUP00000062518	ENSMMUP00000012809	Uncharacterized protein.	C-C motif chemokine.	0.968
CCL24	CCL27	ENSMMUP00000062518	ENSMMUP00000027364	Uncharacterized protein.	Small-inducible cytokine A27.	0.651
CCL24	CCR1	ENSMMUP00000062518	ENSMMUP00000072210	Uncharacterized protein.	C-C chemokine receptor type 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.	0.828
CCL24	CCR2	ENSMMUP00000062518	ENSMMUP00000070568	Uncharacterized protein.	C-C chemokine receptor type 2; Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (By similarity). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity) Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B (By similarity). Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation (By similari [...]	0.807
CCL24	CCR3	ENSMMUP00000062518	ENSMMUP00000006084	Uncharacterized protein.	C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1.	0.960
CCL24	CXCL10	ENSMMUP00000062518	ENSMMUP00000027500	Uncharacterized protein.	C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family.	0.608
CCL24	CXCL11	ENSMMUP00000062518	ENSMMUP00000066782	Uncharacterized protein.	C-X-C motif chemokine.	0.956
CCL24	CXCL12	ENSMMUP00000062518	ENSMMUP00000035953	Uncharacterized protein.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.584
CCL24	CXCL9	ENSMMUP00000062518	ENSMMUP00000045039	Uncharacterized protein.	C-X-C motif chemokine ligand 9.	0.626
CCL27	CCL13	ENSMMUP00000027364	ENSMMUP00000012809	Small-inducible cytokine A27.	C-C motif chemokine.	0.958