STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTCFTranscriptional repressor CTCF isoform 1. (727 aa)    
Predicted Functional Partners:
RAD21
Double-strand-break repair protein rad21 homolog.
   
 0.958
STAG2
Cohesin subunit SA-2 isoform a.
   
 
 0.922
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.862
SMC3
Structural maintenance of chromosomes protein.
   
 0.848
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.811
NIPBL
Nipped-B protein.
   
  
 0.794
SMCHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1.
   
  
 0.784
SMC1A
Structural maintenance of chromosomes protein.
   
 
 0.772
PLS3
Uncharacterized protein.
      
 0.769
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.
    
 0.768
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.