Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM227BFamily with sequence similarity 227 member B. (505 aa)    
Predicted Functional Partners:
LRRIQ3
Leucine rich repeats and IQ motif containing 3.
  
   
 0.648
RNF144A
RBR-type E3 ubiquitin transferase.
      
 0.541
VXN
Vexin.
      
 0.538
TMEM126B
Transmembrane protein 126B isoform a.
      
 0.478
KIFC3
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.453
KIF25
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.453
XPO4
Exportin 4.
      
 0.436
RAPGEF5
Rap guanine nucleotide exchange factor 5.
      
 0.412
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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